Gene mutations are caused by a change in the sequence of a DNA segment representing a gene. The smallest portion of DNA which undergoes mutation is called muton. Every organism has certain genes that mutate more frequently and some genes which suppresses mutations. Usually, mutations are forward type in which wild or normal type change to new mutant genotype, whereas in reverse/ backward type mutant genome change to the wild type. So take this quiz and check your knowledge about gene mutation.
1. Gene mutation can occur in...
A. Somatic cells
B. Germinal cell
C. Both of these
D. None of these
2. What kind of mutation is very rare?
A. One gene mutate at a time
B. Mass mutation
C. Both of these
D. None of these
3. Mostly gene mutations are recessive so they Express only in...
A. Heterozygous form
B. Heterozygous and homozygous form
C. Homozygous form
D. None of these
4. Gene mutations causing a change in single nucleotide are called...
A. Gross mutations
B. Copy error mutation
C. Simple mutation
D. Point mutation
5. Which one of the following is the example of point mutation?
A. Leukaemia
B. Night blindness
C. Edward syndrome
D. Sickle Cell anaemia
6. Sometimes two acrocentric chromosomes break at the kinetochore and join to form one metacentric chromosome, it is called...
A. Robertsonian translocation
B. Inversion
C. Copy error mutation
D. Gross mutation
7. Gene mutation causing a change in a large number of nucleotides is called...
A. Point mutation
B. Gross mutation
C. Copy error mutation
D. Inversion
8. The change in the basic sequence of cistron in reverse order is called...
A. Transition
B. Transversion
C. Substitution
D. Inversion
9. Most of the gene mutations occur during...
A. Translation of DNA
B. Replication of DNA
C. Replacement of DNA
D. Trans version of DNA
10. One purine is replaced by another purine or one pyrimidine by another pyrimidine is called...
A. Transition
B. Transversion
C. Both of these
D. None of these
11. In transversion, cytosine is substituted by...
A. Guanine
B. Adenine
C. Thymine
D. Uracil
12. Which one of the following occurs due to reciprocal translocation between the Philadelphia chromosome with the long arm of 9th chromosome?
A. Sickle Cell anaemia
B. Chronic myeloid leukemia
C. Turner's syndrome
D. Down's syndrome
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